The Apothecary Diaries Season 2 – Release Dates, Episodes and Guide

The Apothecary Diaries Season 2 returned to screens in January 2025, continuing the story of Maomao, the cunning imperial pharmacist whose sharp intellect has made her indispensable to the emperor’s court. Following a successful first season that earned praise for its blend of mystery, historical intrigue, and medical drama, the second installment expanded the narrative across 24 episodes released weekly through Crunchyroll.

Season 2 picked up where the story left off, diving deeper into the complex political machinations of the palace while introducing new mysteries for Maomao to unravel. The series maintained its distinctive tone, balancing moments of tension with humor and the protagonist’s unique perspective on courtly affairs. Fans eagerly anticipated each Friday’s release as new episodes brought fresh developments to the ongoing narrative.

This guide consolidates everything known about The Apothecary Diaries Season 2, including release dates, streaming platforms, episode details, and confirmed information about future installments.

When Did The Apothecary Diaries Season 2 Air?

The Apothecary Diaries Season 2 premiered on January 10, 2025, with new episodes released weekly on Fridays via Crunchyroll. The season concluded on July 4, 2025, completing a run of 24 episodes numbered as episodes 25 through 48, directly continuing from season 1’s numbering system. Initial episode releases occurred at approximately 9:15 to 10:15 AM PT (5:15 PM BST), with the final episode streaming at 10:15 AM PT / 12:15 PM ET / 5:15 PM BST on premiere day.

Season 2 Overview

Key Facts About the Season

• The season aired in two cours, with Cour 2 beginning around April 4, 2025
• All episodes are available on Crunchyroll in subtitled Japanese with English dubs released approximately two weeks later
• The season continues the story directly from season 1’s conclusion
• English dub releases concluded in mid-July 2025, with the final dubbed episode releasing on July 11, 2025
• The series blends historical fiction, mystery, and medical drama genres
• TOHO Animation Studio and OLM shared production responsibilities for the season

At a Glance

Where to Watch The Apothecary Diaries Season 2

Crunchyroll serves as the primary streaming platform for The Apothecary Diaries Season 2, offering both subtitled and dubbed formats for viewers worldwide. The platform provides access across the Americas, Europe, Africa, Oceania, the Middle East, and the Commonwealth of Independent States, making it the most widely available option for international audiences.

Crunchyroll

As the official home of both seasons, Crunchyroll streams The Apothecary Diaries Season 2 in multiple languages. New episodes become available with Japanese subtitles shortly after the Japanese broadcast, typically in the morning hours for North American viewers. English dubbed versions follow approximately two weeks later, allowing viewers to choose their preferred viewing experience. The series page on Crunchyroll lists all episodes and provides streaming information.

Netflix Availability

Netflix availability for season 2 remains unconfirmed across regions where Crunchyroll holds licensing agreements. While some viewers have explored alternative methods to access the series through region-specific Netflix libraries, official confirmation of season 2 being added to Netflix has not been established based on available information.

Other Platforms

Prime Video may carry the series in certain territories through Crunchyroll’s distribution agreements. MyAnimeList functions primarily as a database and community platform rather than a streaming service, providing episode information and fan discussions rather than video content. No official announcements have confirmed Hulu or other major platforms as streaming sources for season 2.

The Apothecary Diaries Season 2 Episode Guide

Season 2 spans 24 episodes, continuing the numbering from season 1 to create a continuous episode count. Each episode carries a title reflecting its content, ranging from straightforward descriptors to cryptic phrases that hint at the mysteries within. The Wikipedia episode list provides comprehensive coverage of episode titles, air dates, and runtime information.

Cour 1 Episode Schedule

• Episode 25 (E1): “Maomao and Maomao” – January 10, 2025
• Episode 26 (E2): “Caravan” – January 17, 2025
• Episode 27 (E3): “Corpse Fungus” – January 24, 2025
• Episode 28 (E4): “Mirrors” – January 31, 2025
• Episode 29 (E5): “Moon Fairy” – February 7, 2025
• Episode 30 (E6): “The Crystal Pavilion, for the Third Time” – February 14, 2025
• Episode 31 (E7): “The Shrine of Choosing” – February 21, 2025
• Episode 32 (E8): “The Empress Dowager” – February 28, 2025
• Episode 33 (E9): “The Late Emperor” – March 7, 2025
• Episode 34 (E10): “A Ghost Story” – March 14, 2025
• Episode 35 (E11): “The Hunt” – March 21, 2025
• Episode 36 (E12): “Ka Zuigetsu” – March 28, 2025

Cour 2 Episode Schedule

• Episode 37 (E13): “The Baths” – April 4, 2025
• Episode 38 (E14): “The Dancing Ghost” – April 11, 2025
• Episode 39 (E15): “Ice” – April 18, 2025
• Episode 40 (E16): “Festering Resentment” – April 25, 2025
• Episode 41 (E17): “The Fox Village” – May 2, 2025
• Episode 42 (E18): “Lantern Plant” – May 9, 2025
• Episode 43 (E19): “Festival” – May 23, 2025
• Episode 44 (E20): “The Stronghold” – May 30, 2025
• Episode 45 (E21): “Taibon” – June 6, 2025
• Episode 46 (E22): (Untitled) – June 13, 2025
• Episode 47 (E23): (Untitled) – June 27, 2025
• Episode 48 (E24): (Season Finale) – July 4, 2025

The Apothecary Diaries Season 2 Cast

The Japanese voice cast returned for season 2, bringing their established interpretations to the continuing story. Maomao’s character, voiced by Aoi Yuki, remained central to the narrative, with her sharp observations and pharmaceutical expertise driving much of the plot. The second season introduced additional characters whose voices contributed to the expanding cast list.

English dubbed versions featured a separate voice cast, with performances recorded in English for international audiences. The dubbed versions released approximately two weeks after their subtitled counterparts, following the same pattern established in season 1. The Fandom wiki maintains detailed cast information as the season progressed, though official announcements regarding cast changes or additions remained limited in publicly available sources.

Season 2 Release Timeline

The Apothecary Diaries Season 2 followed a structured release schedule from announcement through completion. Understanding this timeline helps viewers track the series’ progression and plan their viewing accordingly.

1. October 2023: Season 1 premiered, introducing viewers to Maomao and the imperial court setting
2. Post-Season 1: Season 2 was officially announced following the first season’s conclusion
3. January 10, 2025: Season 2 premiered with the episode “Maomao and Maomao”
4. March 28, 2025: First cour concluded with episode 36
5. April 4, 2025: Second cour began with episode 37
6. July 4, 2025: Season 2 concluded with the episode 48 finale at 10:15 AM PT
7. July 11, 2025: Final English dub released (episode 47)

Confirmed vs Unconfirmed Information

Separating verified details from unconfirmed reports helps viewers understand what information is firmly established versus what remains speculative or pending official announcement.

The Apothecary Diaries Season 2 in Context

The Apothecary Diaries series distinguishes itself within the anime landscape by combining historical fiction with mystery elements and pharmaceutical expertise rarely seen in the medium. The series draws from a light novel series by Nuit Sjouj actou, adapting the narrative that follows Maomao, a young woman with extensive medical knowledge who is taken into the imperial palace as a servant.

Season 2 marked a deepening of the political intrigue established in the first season. The narrative expanded beyond individual mysteries to address larger questions about palace politics, court factions, and the various characters’ hidden agendas. The official trailer for Cour 2 highlighted these elements, emphasizing drama, mystery, historical setting, and the medical aspects that define the series.

The series’ reception remained positive throughout season 2, with viewers appreciating the continued focus on Maomao’s cleverness and the gradual revelation of palace secrets. The two-cour structure allowed for a measured pacing that developed both the overarching narrative and individual episodic mysteries.

Sources and Official Information

Multiple sources have documented The Apothecary Diaries Season 2’s release details, episode schedule, and platform availability. Official announcements from Crunchyroll confirmed the premiere date and ongoing episode releases. The official Crunchyroll announcement provided initial streaming information, while subsequent updates addressed the ongoing release schedule.

“The Apothecary Diaries Season 2 premieres January 10, 2025, only on Crunchyroll. Don’t miss it!”

— Crunchyroll Official Announcement, January 2025

The Fandom wiki and Wikipedia maintained comprehensive episode listings throughout the broadcast period, documenting air dates, titles, and cast information. GamesRadar provided episode-by-episode scheduling details, while RadioTimes published streaming times and episode guides for international audiences.

Summary: Everything We Know About Season 2

The Apothecary Diaries Season 2 completed its 24-episode run from January 10 to July 4, 2025, establishing itself as a successful continuation of the first season. Crunchyroll remained the primary streaming platform throughout the broadcast, offering both subtitled and dubbed versions to international audiences. The two-cour structure provided pacing flexibility while maintaining viewer engagement across the extended broadcast period.

The confirmed premiere of Season 3 in October 2026 signals ongoing commitment to adapting the source material, with an animated film also slated for December 2026. For viewers catching up before season 3 arrives, the complete season 2 remains available through Crunchyroll’s streaming service. Similar series exploring historical mysteries and strong female leads include The Rookie Season 7 UK – Release Date and Where to Watch, offering comparable procedural drama elements.

Frequently Asked Questions